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Verified — all release criteria met
released

Certificate of analysis

MOTS-c

Lot CP-MOTSC-2605B · 20 mg

98.75 %

HPLC purity

Spec ≥ 98.0 %

87.6 %

Net peptide content

By amino acid analysis

< 0.28

Endotoxin (EU/mg)

Spec < 5.0 EU/mg

Provenance

Testing laboratory
Colmaric Analyticals
Accreditation
ISO/IEC 17025:2017
Country of synthesis
United States
Manufactured
May 12, 2026
Release tested
May 21, 2026 (4 months ago)
Retest date
May 11, 2028
CAS number
1627580-64-6
Molecular formula
C101H152N28O22S2
Theoretical mass
2174.60 Da
Observed mass (LC-MS)
2174.68 Da (Δ 0.08 Da)

Assay results

Every line the release panel ran for this lot, with the method, the acceptance criterion and the measured value — not a pass mark alone.

Certificate of analysis — assay results
MethodParameterSpecificationResult
RP-HPLC (UV 214 nm)Purity (area %)≥ 98.0 %98.75 %Pass
LC-MS (ESI+)Identity — observed mass2174.60 ± 1.0 Da2174.68 DaPass
Amino acid analysisNet peptide content≥ 80.0 %87.6 %Pass
Karl FischerWater content≤ 8.0 %1.86 %Pass
Ion chromatographyResidual TFA≤ 1.0 %0.11 %Pass
LAL kinetic chromogenicBacterial endotoxin< 5.0 EU/mg< 0.28 EU/mgPass
USP <71> membrane filtrationSterilityNo growthNo growthPass
Visual / USP <790>AppearanceWhite to off-white cake, free of visible particulatesConformsPass

Sequence

H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

Handling for this lot

Appearance
White lyophilised powder
Storage
-20 °C lyophilised, protected from light
Reconstitution
Two methionine residues make this sequence oxidation-prone. Minimise headspace air on stored stock.

Other lots of MOTS-c

Compare batch to batch. Consistency across lots is a stronger signal than any single certificate.

Research use only. This certificate describes material supplied strictly for laboratory research. It is not a drug, food, cosmetic or medical device, has not been evaluated by the FDA, and is not intended for human or veterinary administration of any kind.