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BPC-157

Body protection compound, gastric pentadecapeptide

A 15-residue gastric juice derived peptide and the single most-requested compound in research supply. Stable in aqueous solution, which is unusual for a peptide this size.

Current lot verified

CP-BPC157-2607A · tested Jul 9, 2026

99.70 %

HPLC purity

Read this lot’s certificate

About BPC-157

BPC-157 is a pentadecapeptide sequence isolated from a protein found in human gastric juice. Its research profile is unusually broad — tendon and ligament fibroblast models, gastrointestinal mucosal work, angiogenesis assays and nitric oxide pathway studies all use it — and the breadth is part of why it draws scepticism as well as interest. The mechanistic thread most consistently reported is upregulation of VEGFR2 signalling and downstream endothelial tube formation.

What makes it practical to work with is stability: unlike most peptides of comparable length, BPC-157 tolerates aqueous solution and low pH without rapid degradation, which is presumably a consequence of where it came from. That does not mean it is indefinitely stable, and it does not mean every vial sold under the name contains it. The acetate and arginine salt forms are both in circulation and behave differently on reversed phase; our certificate states which salt form the lot is, because a purity number without a salt form is not a complete answer.

Published research areas

  • Tendon and ligament fibroblast models
  • Gastrointestinal mucosal research
  • Angiogenesis and VEGFR2 signalling
  • Nitric oxide pathway studies

Specifications

CAS number
137525-51-0
Molecular formula
C62H98N16O22
Molecular weight
1419.53 g/mol
Release specification
≥ 99.0 % by HPLC
Appearance
White lyophilised powder
Solubility
Freely soluble in water, saline and bacteriostatic water
Storage
-20 °C lyophilised. Reconstituted stock stable at 2–8 °C for 30 days.
Format
lyophilized vial

Sequence

H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH

Handling and reconstitution

Dissolves quickly and completely. Persistent cloudiness after two minutes of gentle swirling is a red flag worth reporting.

Storage: -20 °C lyophilised. Reconstituted stock stable at 2–8 °C for 30 days.

Full reconstitution and storage reference

Lot history

Every released lot of this compound, oldest kept on file. Average across 3 lots: 99.50 %.

LotStrengthPurityTestedLaboratory
CP-BPC157-2607A5 mg99.70 %Jul 9, 2026Aurum BioanalyticsCertificate →
CP-BPC157-2605B10 mg99.17 %May 10, 2026Aurum BioanalyticsCertificate →
CP-BPC157-2602C20 mg99.62 %Feb 27, 2026Colmaric AnalyticalsCertificate →

Selected literature

Listed for orientation. Citation is not endorsement of any outcome, and no claim is attached to any of these works.

  • Stable gastric pentadecapeptide BPC 157 and tendon healing

    Journal of Orthopaedic Research

  • BPC 157 and the nitric oxide system

    Current Pharmaceutical Design

Questions about this compound

  • Acetate salt as standard, stated explicitly on every lot certificate. The arginine salt is available on request for work where acetate interferes with the assay. The two are not interchangeable in quantitative work because net peptide content differs.

  • Our stability data supports 30 days at 2–8 °C with less than 2 % loss by HPLC. That is longer than most peptides of this length and is a genuine property of the sequence, not a marketing figure — the stability run is on the certificate.

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